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Silymarin Extract

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Silymarin Extract

Product Overview

● Basic Product Information

• Product Name: Silymarin Extract

• Latin Name: Silybum marianum (L.) Gaertn.

• Plant Part Used: Mature and dried fruits (seeds) of Silybum marianum

● Product Definition

Manufactured from mature dried silybum fruits through impurity removal and degreasing, low-temperature ethanol extraction, resin enrichment and purification, concentration, and aseptic spray drying. The product completely retains the natural compound silymarin system, including silybin, isosilybin, silychristin, and silydianin. It contains no artificially blended monomers or exogenous auxiliary materials. Featuring hepatocyte protection, antioxidant activity, metabolic regulation and anti-inflammatory repair effects, it serves as a mature homologous medicinal and edible core raw material for liver protection. Different from coarse powder and single monomer blended products, its multi-component synergistic effect achieves better performance, precisely adapting to liver injury protection, staying-up metabolism conditioning and sub-health maintenance demands.

● Basic Product Parameters

• Raw Material Source: 100% extracted from silybum fruits, free of starch, dextrin and other exogenous additives.

• Processing Grade: Low-temperature first-grade refined extract, no high-temperature degradation or artificial blending; free of impurities, solvent residues, excessive heavy metals and pesticide residues.

• Core Indicators: Total silymarin (UV): 30%-80%; Silybin A+B (HPLC): 20%-50%, with balanced active components and excellent antioxidant capacity.

• Physical and Chemical Properties: Lipophilic fine powder, soluble in organic solvents; water-dispersible and phospholipid-compounded specifications are customizable for multiple dosage forms.

• Applicable Dosage Forms: Tablets, capsules, soft capsules, solid beverages, pressed candies, compound powders and other forms.

• Storage Properties: Sealed and light-proof, moisture-proof; long-term stable storage in cool and dry places with stable active ingredients.



Core Advantage

● Core Product Advantages

• Premium Origin & High Purity Activity:

Adopts high-quality raw materials from high-yield producing areas with plump grains and high activity, ensuring raw material purity from the source.

• Low-temperature Activity Lock & Natural Components:

Whole-process low-temperature technology and resin impurity removal completely retain four core active components. The natural proportion and synergistic effect outperform artificially blended monomers.

• Zero-additive Purity & Full Compliance:

Free of blending, fillers, pigments, flavors, preservatives and harmful additives. Strictly controls residues and microorganisms, complying with domestic health food standards and international pharmacopoeia specifications.

• Strong Compatibility & Full-scenario Adaptation:

Stable physicochemical properties with high acid and alkali tolerance. Applicable for single use or compound formulation, adapting to water-based, oil-based and solid systems for full-category product development.

• Standardized Production & Stable Batch Quality:

Produced in 100,000-class GMP workshops with HPLC/dual UV detection. Key indicators are strictly controlled to ensure consistent batch quality, full compliance and traceability.


Core Product Characteristics

● Physical Quality Characteristics

Uniform fine powder from light yellow to tan with natural color, loose, delicate and good fluidity. It has an elegant natural herbal fragrance without peculiar odor. Conventional lipophilic formula is water-insoluble; modified water-dispersible formula dissolves evenly without precipitation; phospholipid-compounded formula delivers significantly improved absorption. Featuring pure and stable quality, it is superior to crude extracts with many impurities and unstable properties.

● Active Structural Characteristics

Possesses core advantages of multi-component synergy, targeted liver protection, strong antioxidant capacity and high stability. Four-dimensional active components compound to deliver comprehensive effects far better than single monomers. With high processing resistance and stability, it targets hepatocytes precisely and makes up for the single-effect defect of ordinary antioxidant raw materials.

● Formulation Application Characteristics

High compatibility with few incompatibility risks. Lipophilic version adapts to solid preparations; water-soluble version fits beverages and solid drinks; phospholipid version applies to high-end high-absorption products. Compatible with various industrial processes, meeting the demands of mass production and high-end refined product development.

● Storage Stability Characteristics

Adopts food-grade high-barrier light-proof packaging to isolate light, oxygen and moisture and prevent oxidation and moisture absorption. Storable at room temperature in cool conditions without freezing. Flexible packaging specifications adapt to research and development, pilot test and mass production scenarios.


Core Active Ingredients & Functional Mechanisms

● Core Functional Ingredients

Silymarin (flavonolignan complex), composed of silybin, isosilybin, silychristin and silydianin. The synergistic effect of multiple components forms the core material basis for anti-oxidation, liver protection, anti-inflammation and metabolic regulation.

● Free Radical Scavenging & Powerful Anti-oxidative Stress (Natural Antioxidant Mechanism)

Directly scavenges reactive oxygen free radicals and inhibits lipid peroxidation. Activates endogenous antioxidant enzymes such as SOD and glutathione to build a dual antioxidant barrier. Effectively relieves oxidative damage caused by staying up late and high-fat diet, and delays cellular aging.

● Stabilize Hepatocyte Membrane & Block Extrinsic Liver Damage (Liver Barrier Protection Mechanism)

Stabilizes hepatocyte membrane structure and optimizes permeability to form a protective barrier. Blocks the invasion of alcohol, toxins and harmful substances, reduces the risk of chemical and metabolic liver damage, and maintains normal liver physiological functions.

● Activate Cellular Activity & Promote Hepatocyte Repair and Regeneration (Cell Repair Mechanism)

Silybin activates hepatocyte polymerase activity, accelerates protein synthesis and metabolism, promotes the repair and regeneration of damaged hepatocytes, alleviates liver metabolic fatigue caused by staying up late, drinking and irregular lifestyles, and restores liver function.

● Inhibit Inflammatory Pathways & Relieve Hepatic Inflammatory Damage (Anti-inflammatory Repair Mechanism)

Regulates the NF-κB signaling pathway, down-regulates pro-inflammatory factors such as TNF-α and IL-6, and inhibits chronic low-grade liver inflammation. Suppresses abnormal activation of hepatic stellate cells, slows liver fibrosis progression and repairs hepatic inflammatory damage.

● Regulate Lipid Metabolism & Reduce Hepatic Metabolic Burden (Metabolic Conditioning Mechanism)

Modulates lipid metabolism, accelerates lipid decomposition, reduces hepatic lipid accumulation and relieves liver metabolic pressure. Long-term mild conditioning maintains liver metabolic homeostasis.


Product Applications

● Health Food R&D Application

Core raw material for blue-label liver-protective health foods, applied in capsules, tablets, soft capsules and other formulations. Suitable for crowds with long-term drinking, staying up late and heavy liver metabolic burden.

● Dietary Supplement FMCG Application

Widely used in domestic and international dietary supplement development. Positioned as natural herbal liver protection and staying-up maintenance ingredients, it replaces synthetic antioxidants to develop tablets, capsules and compound powders for sub-health population daily maintenance.

● Functional Food Deep Processing Application

Applicable for pressed candies, solid beverages, health powders and other functional foods; water-soluble version adapts to functional drinks. Often compounded with pueraria root, curcumin and other ingredients to develop liver-protective and metabolic conditioning foods.

● High-end Compound Formula R&D Application

Suitable for scientific research institutions and enterprise new product development. Provides standardized raw materials with different contents and processing techniques to support the R&D of high-end antioxidant and liver-protective compound products.

● Export-oriented Raw Material Application

Complies with USP and EP pharmacopoeia standards with complete qualification documents. Supplied in bulk to global health food and dietary supplement manufacturers, serving as one of China’s core exported liver-protective plant raw materials.

● Pet Health Nutrition Application

Applied in pet liver-protective powders, tablets and ointments to improve pet metabolic disorders, greasy diet burden and drug-induced liver damage with natural herbal solutions.


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