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Ginkgo Biloba Leaf Extract

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Ginkgo Biloba Leaf Extract

Product Overview

● Basic Product Information

➢ Product Name: Ginkgo Biloba Leaf Extract

➢ Latin Name: Ginkgo biloba L.

➢ Plant Part Used: Dried leaves of Ginkgoaceae Ginkgo biloba

● Product Definition

Manufactured from dried ginkgo biloba leaves via sorting-impurity removal, ethanol-water composite extraction, macroporous resin enrichment-purification, ginkgolic acid removal, vacuum concentration and aseptic spray-drying. The product retains natural active components of ginkgo biloba leaf (ginkgo flavonol glycosides, terpene lactones) with strictly controlled ginkgolic acid residues, without artificial monomer blending or extra exogenous auxiliary materials. It exerts multiple physiological effects including anti-oxidation, anti-inflammation and microcirculation regulation, and is a widely-used botanical functional raw material worldwide. Compared with crude ginkgo leaf powder and monomer-blended products, multi-component synergistic effects are superior, suitable for sub-health maintenance of microcirculation care and anti-oxidation.

● Basic Product Parameters

➢ Raw Material Source: 100% extracted from ginkgo biloba leaves, free of starch, dextrin and other exogenous additives.

➢ Processing Grade: Low-temperature first-grade refined extract. Toxic ginkgolic acid is thoroughly removed; high-temperature-caused degradation of flavonoids and lactones is avoided; no artificial blending. Free of impurities, solvent residues, excessive heavy metals and pesticide residues.

➢ Core Indicators: Ginkgo flavonol glycosides (HPLC) 24%, terpene lactones 6%, ginkgolic acid <5ppm. Multiple customized grades are available with balanced activity and excellent anti-oxidation performance.

➢ Physical and Chemical Properties: Yellow-brown to brown fine powder. Water-dispersible encapsulated grades are available for multiple dosage-form development.

➢ Applicable Dosage Forms: Tablets, capsules, soft capsules, solid beverages, pressed candies, compound powders and others.

➢ Storage Properties: Sealed, light-proof and moisture-proof. Store in cool and dry place for long-term stable activity.

● Core Product Advantages

➢ Authentic Raw Material, High-purity & High-activity:

Select mature ginkgo leaves from high-quality producing areas. Strict control over harvesting and processing guarantees sufficient intrinsic contents of flavonol glycosides and terpene lactones, and strictly controls impurities and harmful components from the source.

➢ Low-temperature Activity Lock, Natural Components:

Adopt full-process low-temperature extraction, resin enrichment and acid-removal processes to fully preserve natural ratio of flavonol glycosides and terpene lactones. Natural compound system delivers better synergistic benefits than pure monomer blending.

➢ Zero-adulteration Purity, Safe & Compliant:

Free of blending, fillers, pigments, flavors, preservatives and harmful auxiliaries. Strictly control ginkgolic acid, solvent residues and microorganisms, complying with health-food and export pharmacopoeia standards.

➢ Strong Compatibility, Full-scenario Adaptation:

Ethanol-soluble; encapsulated modification improves water-dispersibility. Good acid-alkali tolerance. Can be used alone or compounded with other botanical raw materials, adaptable to water-based, oil-based and solid-form systems for full-category product development.

➢ Standardized Production, Stable Batch Quality:

Produced in 100,000-class GMP workshop. Tested by HPLC and UV dual-methods. Key indicators including flavonol glycosides, terpene lactones and ginkgolic acid are strictly controlled for uniform batch quality and full traceability.


Core Advantage

Core Product Characteristics

● Physical Quality Characteristics

Uniform fine powder from yellow-brown to brown with natural plant color, loose, delicate and good fluidity. It bears faint herbal odor characteristic of ginkgo biloba leaf, free of mildewed or scorched peculiar odor. Conventional grades show excellent ethanol-solubility; encapsulated modified grades achieve water-dispersibility. Pure and stable quality, superior to crude ginkgo leaf powder.

● Active Structural Characteristics

Multi-component synergy, microcirculation regulation and powerful anti-oxidation. Dual-system compound of flavonol glycosides and terpene lactones achieves better comprehensive performance than single monomer. Fair processing tolerance, making up for the shortcoming of single-target effect of ordinary single-function raw materials.

● Formulation Application Characteristics

Good formulation compatibility with few incompatibility risks. Ethanol-soluble grades fit capsules, soft capsules and tablets; encapsulated water-dispersible grades apply to solid beverages and functional candies. Long-time high-temperature treatment shall be avoided during processing. Adaptable to various processes to meet mass-production and high-end development demands.

● Storage Stability Characteristics

Food-grade high-barrier light-proof packaging isolates light, oxygen and moisture to prevent moisture absorption and oxidation. Store at cool room temperature without freezing. Flexible packaging specifications support lab-scale R&D, pilot test and large-scale production.


Core Active Ingredients and Functional Mechanisms

● Core Functional Ingredients

Ginkgo biloba leaf active complex, mainly ginkgo flavonol glycosides (quercetin, kaempferol, isorhamnetin) and terpene lactones (ginkgolide A/B/C, bilobalide). Synergy of multiple components forms the material basis for anti-oxidation, anti-inflammatory repair and microcirculation regulation.

● Free Radical Scavenging & Potent Anti-oxidative Stress (Natural Antioxidant Mechanism)

Ginkgo flavonol glycosides directly scavenge reactive-oxygen free radicals and inhibit lipid peroxidation. They up-regulate endogenous antioxidant enzymes such as SOD and glutathione to build dual anti-oxidant barriers, relieve oxidative damage and delay cellular senescence.

● Protect Vascular Endothelium & Improve Microcirculation (Microcirculation Regulation Mechanism)

Terpene lactones cooperate with flavonol glycosides to protect vascular endothelial cells, regulate vascular tension and improve body microcirculation perfusion, representing the characteristic target of this raw material.

● Regulate Inflammatory Pathways & Relieve Low-grade Bodily Inflammation (Anti-inflammatory Repair Mechanism)

Modulate NF-κB signaling pathway, down-regulate release of pro-inflammatory factors including TNF-α and IL-6, suppress chronic low-grade inflammation in vivo and mitigate inflammatory damage induced by oxidative stress.

● Antagonize Platelet-Activating Factor & Maintain Blood Flow Status (Blood Flow Regulation Mechanism)

Ginkgolides antagonize platelet-activating factor (PAF), assist in maintaining normal blood rheology and keep unobstructed microcirculation.

● Preserve Cell Membrane Integrity & Reduce Oxidative Damage (Cell-protection Mechanism)

Flavonol glycosides and terpene lactones jointly act on cell membranes, mitigate free-radical attack against membrane lipids, maintain cell-membrane structural integrity and reduce cell damage induced by external oxidative stimuli.


Product Applications

● Health Food R&D Application

Raw material for microcirculation-care health foods, applied in capsules and tablets for crowds requiring microcirculation maintenance and anti-oxidation.

Note: Domestic product development shall comply with relevant regulations; ginkgolic acid content, dosage and raw-material source shall be strictly controlled.

● Dietary Supplement FMCG Application

Classic botanical raw material for domestic and overseas dietary supplements, featured with microcirculation care and anti-oxidation. Developable into tablets, capsules and powders for sub-health populations.

● Functional Food Deep-processing Application

Applied in pressed candies, solid beverages and health-care powders. Often compounded with grape seed extract and bamboo leaf flavonoids to manufacture anti-oxidation and circulation-care functional foods.

● High-end Compound Formula R&D Application

For scientific-research institutes and enterprise new-product development. Standardized raw materials with different ratios are available to support high-end compound-product development for microcirculation care and anti-oxidation purposes.

● Export-oriented Raw Material Compliance Application

Meets USP and EP pharmacopoeia requirements with complete qualification documents. Bulk-exported worldwide, it is a mainstream botanical microcirculation-regulating raw material in global markets.

● Pet Health Nutrition Application

Full safety and dosage assessment shall be completed for pet-formula adoption. After safety evaluation, limited addition is allowed in pet nutritional tablets and powders for anti-oxidation direction.


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